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Optimal Selection of IFN-α-Inducible Genes to Determine Type I Interferon Signature Improves the Diagnosis of Systemic Lupus Erythematosus

12 Mar 2023

Abstract excerpt

Systemic lupus erythematosus (SLE) is a chronic autoimmune disease characterized by the production of autoantibodies specific to self-molecules in the nucleus, cytoplasm, and cell surface. The diversity of serologic and clinical manifestations observed in SLE patients challenges the development of diagnostics and tools for monitoring disease activity. Elevated type I interferon signature (IFN- I) in SLE leads to...

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Immune Cell Function and Interaction
Systemic Lupus Erythematosus Research
T-cell and B-cell Immunology

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 36979843
DOI: 10.3390/biomedicines11030864

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

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