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Article

Variation in the characteristics of 10 mouse-passaged scrapie lines derived from five scrapie-positive sheep.

The Journal of general virology - 1 Feb 1991

Carp R I, Callahan S M

Abstract excerpt

Ten mouse-passaged scrapie lines were initiated from five sheep with clinical scrapie. Of the lines, five were initiated and passaged exclusively in mice with the s7s7 genotype and the remaining five lines were initiated in mice with the p7p7 genotype, with two of these lines subsequently being passaged exclusively in p7p7 mice and two being passaged mainly in p7p7 mice. Lines were passaged three or four times...

Topics

Animals
Body Weight
Brain
Genetic Variation
Genotype
Male
Mice
Mice, Inbred C57BL
Prions
Scrapie
Serial Passage
Sheep

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Identifiers

PMID: 1899690
DOI: 10.1099/0022-1317-72-2-293

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-1899690-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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