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Article

Scrapie strain variation and mutation.

British medical bulletin - 1 Oct 1993

Bruce M E

Abstract excerpt

There are many strains of scrapie, distinguishable by their disease characteristics in genetically-defined mice. Numerous distinct strains have been isolated in the same mouse strain, indicating that scrapie agents have an informational molecule, independent of the host. Strain characteristics are stable on serial mouse passage under constant passaging conditions. However, changes in the species or mouse genotype...

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PMID: 8137131
DOI: 10.1093/oxfordjournals.bmb.a072649

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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