Article
Strain characterization of natural sheep scrapie and comparison with BSE.
The Journal of general virology - 1 Mar 2002
Bruce Moira E, Boyle Aileen, Cousens Simon, McConnell Irene, Foster James, Goldmann Wilfred, Fraser Hugh
Abstract excerpt
Scrapie was transmitted to mice from ten sheep, collected in the UK between 1985 and 1994. As in previous natural scrapie transmissions, the results varied between scrapie sources in terms of the incidence of disease, incubation periods and neuropathology in challenged mice. This contrasted with the uniformity seen in transmissions of BSE to mice. The scrapie and BSE isolates were characterized further by serial...
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