Promoter independence as a feature of most skin papillomas in SENCAR mice.

Article

Promoter independence as a feature of most skin papillomas in SENCAR mice.

Cancer research - 1 Feb 1991

Aldaz C M, Conti C J, Chen A, Bianchi A, Walker S B, DiGiovanni J

Abstract excerpt

In the present study, the fate of individual papillomas induced by initiation-promotion on the backs of SENCAR mice was monitored after discontinuation of limited promoter treatment. Groups of 40 SENCAR mice each were initiated by a single topical application of 7,12-dimethylbenz[a]anthracene (DM...

Topics

9,10-Dimethyl-1,2-benzanthracene
Animals
Genes, ras
Mice
Mutation
Neoplasm Regression, Spontaneous
Papilloma
Skin Neoplasms
Tetradecanoylphorbol Acetate
Time Factors

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