Article
Only a subset of 12-O-tetradecanoylphorbol-13-acetate-promoted mouse skin papillomas are promotable by benzoyl peroxide.
Mutation research - 14 Apr 2004
Mancuso Mariateresa, Pazzaglia Simonetta, Tanori Mirella, Rebessi Simonetta, Di Majo Vincenzo, Covelli Vincenzo, Saran Anna
Abstract excerpt
The two-stage skin carcinogenesis model of initiation and promotion in Carcinogenesis-susceptible (Car-S) mice has been used to investigate the pathways of promotional activity of 12-O-tetradecanoylphorbol-13-acetate (TPA), a phorbol ester tumor promoter, and benzoyl peroxide (BzPo), a free radical-generating compound. To test whether distinct populations of 9,10-dimethyl-1,2-benzanthracene (DMBA)-initiated...
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