Article
Promotion of skin tumors by 12-O-tetradecanoylphorbol-13-acetate in two generations of descendants of male mice exposed to X-ray irradiation.
Mutation research - 1 Jun 1993
Vorobtsova I E, Aliyakparova L M, Anisimov V N
Abstract excerpt
Progeny of outbred SHR male mice intact or exposed to a single dose of whole-body X-ray irradiation (4.2 Gy) was painted twice a week for 24 weeks from the age of 4 months with acetone or with acetone solution of 6.15 micrograms 12-O-tetradecanoylphorbol-13-acetate (TPA). The incidence and number...
Topics
- 9,10-Dimethyl-1,2-benzanthracene
- Animals
- Cocarcinogenesis
- Female
- Fetus
- Genes, ras
- Male
- Mice
- Mutation
- Neoplasms, Radiation-Induced
- Papilloma
- Sex Factors
- Skin Neoplasms