Article
Alterations in protein kinase C isozymes alpha and beta 2 in activated Ha-ras containing papillomas in the absence of an increase in diacylglycerol.
Carcinogenesis - 1 Jul 1992
Mills K J, Bocckino S B, Burns D J, Loomis C R, Smart R C
Abstract excerpt
The levels of protein kinase C (PKC) activity, PKC isozymes, as well as the level of endogenous diacylglycerols (DAG) were examined in early emergence mouse skin papillomas and compared to the levels in the epidermis. The papillomas were derived from a two-stage carcinogenesis protocol in which m...
Topics
- 9,10-Dimethyl-1,2-benzanthracene
- Amino Acid Sequence
- Animals
- Codon
- Diglycerides
- Female
- Genes, ras
- Immune Sera
- Isoenzymes
- Mice
- Mice, Inbred Strains
- Molecular Sequence Data
- Mutation
- Papilloma
- Peptides
- Protein Kinase C
- Skin
- Skin Neoplasms