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Article

Vinculin tail conformation and self-association is independent of pH and H906 protonation.

Biochemistry - 25 Nov 2008

Palmer Sean M, Schaller Michael D, Campbell Sharon L

Abstract excerpt

Vinculin is a highly conserved cytoskeletal protein that localizes to sites of cell adhesion. The tail domain of vinculin (Vt) forms tight autoinhibitory interactions with the head domain and down-regulates vinculin function by obscuring ligand binding sites. Ligand binding is required for both v...

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PMID: 18980387
DOI: 10.1021/bi801764a

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-18980387-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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