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Article

Monomeric and dimeric conformation of the vinculin tail five-helix bundle in solution studied by EPR spectroscopy.

Biophysical journal - 5 Oct 2011

Abé Christoph, Dietrich Franziska, Gajula Prasad, Benz Monique, Vogel Klaus-Peter, van Gastel Maurice, Illenberger Susanne, Ziegler Wolfgang H, Steinhoff Heinz-Jürgen

Abstract excerpt

The cytoskeletal adaptor protein vinculin plays an important role in the control of cell adhesion and migration, linking the actin cytoskeleton to adhesion receptor complexes in cell adhesion sites. The conformation of the vinculin tail dimer, which is crucial for protein function, was analyzed u...

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Identifiers

PMID: 21961604
DOI: 10.1016/j.bpj.2011.08.048
PMCID: PMC3183806

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-21961604-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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