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Article

Vinculin acts as a sensor in lipid regulation of adhesion-site turnover.

Journal of cell science - 1 Apr 2005

Chandrasekar Indra, Stradal Theresia E B, Holt Mark R, Entschladen Frank, Jockusch Brigitte M, Ziegler Wolfgang H

Abstract excerpt

The dynamics of cell adhesion sites control cell morphology and motility. Adhesion-site turnover is thought to depend on the local availability of the acidic phospholipid phosphatidylinositol-4,5-bisphosphate (PIP(2)). PIP(2) can bind to many cell adhesion proteins such as vinculin and talin, but the consequences of this interaction are poorly understood. To study the significance of phospholipid binding to...

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Source

Identifiers

PMID: 15769850
DOI: 10.1242/jcs.01734

Genes

PIP

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Vinculin acts as a sensor in lipid regulation of adhesion-site turnover.PMID 15769850Read ↗

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