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Article

Monoamine oxidase A genotype predicts human serotonin 1A receptor availability in vivo.

The Journal of neuroscience : the official journal of the Society for Neuroscience - 29 Oct 2008

Mickey Brian J, Ducci Francesca, Hodgkinson Colin A, Langenecker Scott A, Goldman David, Zubieta Jon-Kar

Abstract excerpt

The serotonergic system, including the serotonin 1A (5-HT(1A)) receptor, has been implicated in the pathophysiology of a number of neuropsychiatric disorders. Current data show substantial interindividual variation in the regional concentration of this receptor site, the source of which is unclear. Monoamine oxidase A (MAO-A) is a key regulator of serotonin metabolism, and polymorphic variation in the X-linked...

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Identifiers

PMID: 18971477
DOI: 10.1523/JNEUROSCI.2391-08.2008
PMCID: PMC2613649

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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