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Article

Impact of COMT genotype on serotonin-1A receptor binding investigated with PET.

Brain structure & function - 1 Nov 2014

Baldinger Pia, Hahn Andreas, Mitterhauser Markus, Kranz Georg S, Friedl Marion, Wadsak Wolfgang, Kraus Christoph, Ungersböck Johanna, Hartmann Annette, Giegling Ina, Rujescu Dan, Kasper Siegfried, Lanzenberger Rupert

Abstract excerpt

Alterations of the inhibitory serotonin-1A receptor (5-HT1A) constitute a solid finding in neuropsychiatric research, particularly in the field of mood and anxiety disorders. Manifold factors influencing the density of this receptor have been identified, e.g., steroid hormones, sunlight exposure and genetic variants of serotonin-related genes. Given the close interactions between serotonergic and dopaminergic...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Polymorphism, Single Nucleotide

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Share to Receptor, Serotonin, 5-HT1A

Source

Identifiers

PMID: 23928748
DOI: 10.1007/s00429-013-0621-8

Genes

COMT

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

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