Article
Interaction between 5-HTTLPR and 5-HT1B genotype status enhances cerebral 5-HT1A receptor binding.
NeuroImage - 1 May 2015
Baldinger Pia, Kraus Christoph, Rami-Mark Christina, Gryglewski Gregor, Kranz Georg S, Haeusler Daniela, Hahn Andreas, Spies Marie, Wadsak Wolfgang, Mitterhauser Markus, Rujescu Dan, Kasper Siegfried, Lanzenberger Rupert
Abstract excerpt
Serotonergic neurotransmission is thought to underlie a dynamic interrelation between different key structures of the serotonin system. The serotonin transporter (SERT), which is responsible for the reuptake of serotonin from the synaptic cleft into the neuron, as well as the serotonin-1A (5-HT1A) and -1B (5-HT1B) receptors, inhibitory auto-receptors in the raphe region and projection areas, respectively, are...
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