Article
Polymorphisms of serotonin neurotransmission and their effects on antipsychotic drug action.
Pharmacogenomics - 1 Jan 2014
Tang Hao, McGowan Olga O, Reynolds Gavin P
Abstract excerpt
The receptor pharmacology of many antipsychotic drugs includes actions at various serotonin (5-hydroxytryptamine [5-HT]) receptors. The 5-HT neurotransmitter system is thought to be involved in many of the consequences of treatment with antipsychotic drugs, including both symptom response, primarily of negative and depressive symptoms, and adverse effects, notably extrapyramidal side effects and weight gain....
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