Article
Serotonin-related gene polymorphisms and central nervous system serotonin function.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology - 1 Mar 2003
Williams Redford B, Marchuk Douglas A, Gadde Kishore M, Barefoot John C, Grichnik Katherine, Helms Michael J, Kuhn Cynthia M, Lewis James G, Schanberg Saul M, Stafford-Smith Mark, Suarez Edward C, Clary Greg L, Svenson Ingrid K, Siegler Ilene C
Abstract excerpt
Central nervous system (CNS) serotonergic function affects a wide range of biological and behavioral functions affecting health and disease. Our objective in this study was to determine whether functional polymorphisms of the genes that encode for the serotonin transporter promoter (5HTTLPR) and monoamine oxidase A (MAOA-uVNTR) are associated with CNS serotonin turnover-indexed by cerebrospinal fluid levels of...
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