Article
Genetic variation in brain-derived neurotrophic factor is associated with serotonin transporter but not serotonin-1A receptor availability in men.
Biological psychiatry - 1 Sept 2009
Henningsson Susanne, Borg Jacqueline, Lundberg Johan, Bah Jessica, Lindström Mats, Ryding Erik, Jovanovic Hristina, Saijo Tomoyuki, Inoue Makoto, Rosén Ingmar, Träskman-Bendz Lil, Farde Lars, Eriksson Elias
Abstract excerpt
BACKGROUND: The serotonergic system, including the serotonin transporter (5-HTT), which is the target of many antidepressants, seems to be influenced by brain-derived neurotrophic factor (BDNF). METHODS: Positron emission tomography (PET) was used to address, in 25 and 53 healthy volunteers, respectively, the possible association between six polymorphisms in the gene encoding BDNF and the availability of two...
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