Article
A functional polymorphism in the MAOA gene promoter (MAOA-LPR) predicts central dopamine function and body mass index.
Molecular psychiatry - 1 Sept 2006
Ducci F, Newman T K, Funt S, Brown G L, Virkkunen M, Goldman D
Abstract excerpt
Variation in brain monoaminergic activity is heritable and modulates risk of alcoholism and other addictions, as well as food intake and energy expenditure. Monoamine oxidase A deaminates the monoamine neurotransmitters serotonin, dopamine (DA), and noradrenaline. The monoamine oxidase A (MAOA) gene (Xp11.5) contains a length polymorphism in its promoter region (MAOA-LPR) that putatively affects transcriptional...
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