Article
Caffeine acetylator phenotyping during maturation in infants.
Pediatric research - 1 May 1991
Pariente-Khayat A, Pons G, Rey E, Richard M O, D'Athis P, Moran C, Badoual J, Olive G
Abstract excerpt
Caffeine acetylator phenotype was studied during maturation in 54 8- to 447-d-old children hospitalized for minor disease (group A) and in five 3- to 630-d-old children with Pierre Robin syndrome (group B). In group A, the children received 2.5 mg/kg caffeine orally once between birth and 15 mo. Group B patients were chronically treated with caffeine (2.3 to 15.8 mg/kg/d) for prevention of apneas, and the...
Topics
- Acetylation
- Adult
- Age Factors
- Arylamine N-Acetyltransferase
- Caffeine
- Enzyme Induction
- Female
- Humans
- Inactivation, Metabolic
- Infant
- Infant, Newborn
- Liver
