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Article

Susceptibility to Coxsackievirus B3-induced chronic myocarditis maps near the murine Tcr alpha and Myhc alpha loci on chromosome 14.

The American journal of pathology - 1 Mar 1991

Traystman M D, Chow L H, McManus B M, Herskowitz A, Nesbitt M N, Beisel K W

Abstract excerpt

This study was undertaken to determine the genetic control of host susceptibility to coxsackievirus B3 (CVB3)-induced chronic myocarditis in a mouse model. An autosomal recessive autoimmune myocardial disease (amd) gene (possibly more than one gene), which determined susceptibility to CVB3-induced chronic myocarditis in the A/J and DBA/2J inbred mouse strains, was mapped to a segment of chromosome 14. Data from...

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Identifiers

PMID: 1848043
PMCID: PMC1886275

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