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Article

Susceptibility to Coxsackievirus B3-induced chronic myocarditis maps near the murine Tcr alpha and Myhc alpha loci on chromosome 14.

The American journal of pathology - 1 Mar 1991

Traystman M D, Chow L H, McManus B M, Herskowitz A, Nesbitt M N, Beisel K W

Abstract excerpt

This study was undertaken to determine the genetic control of host susceptibility to coxsackievirus B3 (CVB3)-induced chronic myocarditis in a mouse model. An autosomal recessive autoimmune myocardial disease (amd) gene (possibly more than one gene), which determined susceptibility to CVB3-induced chronic myocarditis in the A/J and DBA/2J inbred mouse strains, was mapped to a segment of chromosome 14. Data from...

Topics

Animals
Autoimmune Diseases
Chromosome Mapping
Chronic Disease
Coxsackievirus Infections
Enterovirus B, Human
Genetic Linkage
Genetic Predisposition to Disease
Mice
Mice, Inbred Strains

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Myocarditis

Phenotype

Source

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Identifiers

PMID: 1848043
PMCID: PMC1886275

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-1848043-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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