Article
Two autoimmune diabetes loci influencing T cell apoptosis control susceptibility to experimental autoimmune myocarditis.
Journal of immunology (Baltimore, Md. : 1950) - 15 Feb 2005
Guler Mehmet L, Ligons Davinna L, Wang Yan, Bianco Michael, Broman Karl W, Rose Noel R
Abstract excerpt
The pathogenesis of immune-mediated myocarditis depends on genetic and environmental factors. To study the genetic mechanisms, we have developed a model of experimental autoimmune myocarditis in the A.SW mouse. Here we provide evidence that loci on murine chromosome 6, and possibly chromosome 1,...
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