Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Variation in Galr1 expression determines susceptibility to exocitotoxin-induced cell death in mice.

Genes, brain, and behavior - 1 Jul 2008

Kong S, Lorenzana A, Deng Q, McNeill T H, Schauwecker P E

Abstract excerpt

Inbred strains of mice differ in their susceptibility to excitotoxin-induced cell death, but the genetic basis of individual variation in differential susceptibility is unknown. Previously, we identified a highly significant quantitative trait locus (QTL) on chromosome 18 that influenced susceptibility to kainic acid-induced cell death (Sicd1). Comparison of susceptibility to seizure-induced cell death between...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cell Death
Share to Excitatory Amino Acid Agonists
Share to Hippocampus

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Kainic Acid

Share to Mice, Congenic

Share to Mice, Inbred DBA

Share to Myelin Basic Protein

Share to Neurotoxins

Source

Open in PubMed Open full text

Identifiers

PMID: 18363852
DOI: 10.1111/j.1601-183X.2008.00395.x
PMCID: PMC2836321

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Variation in Galr1 expression determines susceptibility to exocitotoxin-induced cell death in mice.PMID 18363852Read ↗

A quantitative trait locus on chromosome 18 is a critical determinant of excitotoxic cell death susceptibility.Semantic proximity Read ↗

Congenic strains provide evidence that a mapped locus on chromosome 15 influences excitotoxic cell death.Semantic proximity Read ↗

Susceptibility to seizure-induced excitotoxic cell death is regulated by an epistatic interaction between Chr 18 (Sicd1) and Chr 15 (Sicd2) loci in mice.Semantic proximity Read ↗

Genetic control of sensitivity to hippocampal cell death induced by kainic acid: a quantitative trait loci analysis.Semantic proximity Read ↗

Genetic basis of kainate-induced excitotoxicity in mice: phenotypic modulation of seizure-induced cell death.Semantic proximity Read ↗

Fine Mapping of a Dravet Syndrome Modifier Locus on Mouse Chromosome 5 and Candidate Gene Analysis by RNA-Seq.Semantic proximity Read ↗

Comparison of seizure phenotype and neurodegeneration induced by systemic kainic acid in inbred, outbred, and hybrid mouse strains.Semantic proximity Read ↗

A locus on mouse Ch10 influences susceptibility to limbic seizure severity: fine mapping and in silico candidate gene analysis.Semantic proximity Read ↗

Experimental models of multifactorial epilepsies: the EL mouse and mice susceptible to audiogenic seizures.Semantic proximity Read ↗

C57BL/6J and C57BL/6N substrains differentially influence phenotype severity in the Scn1a+/− mouse model of Dravet syndromeSemantic proximity Read ↗

Susceptibility to anthrax lethal toxin-induced rat death is controlled by a single chromosome 10 locus that includes rNlrp1.Semantic proximity Read ↗

Allelic variation on murine chromosome 11 modifies host inflammatory responses and resistance to Bacillus anthracis.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.