Article
Genetic differences in bone marrow-derived lymphoid lineages control susceptibility to experimental autoimmune myocarditis.
Journal of immunology (Baltimore, Md. : 1950) - 1 Jun 2008
Li Haiyan S, Ligons Davinna L, Rose Noel R, Guler Mehmet L
Abstract excerpt
Bone marrow (BM) transplantation has been used to study the cellular basis of genetic control of autoimmune diseases, but conclusions remain elusive due to the contradictory findings in different animal models. In the current study, we found that BM cells from myocarditis-susceptible A.SW mice can render irradiated, myocarditis-resistant B10.S recipient mice susceptible to myosin-induced myocarditis, indicating...
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