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Article

A single mutation at lysine 241 alters expression and trafficking of the D2 dopamine receptor.

Journal of receptor and signal transduction research - 1 Jan 2008

Kim Ok-Jin

Abstract excerpt

Ubiquitination of G protein-coupled receptors has been identified to regulate receptor signal transduction including agonist-induced internalization and sorting of internalized receptor for degradation or for recycling. Using co-immunoprecipitation and immunoblot analysis, I found that the membrane-associated D(2) dopamine receptor (DAR) is mono-ubiquitinated in the absence of an agonist following heterologous...

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Identifiers

PMID: 18946766
DOI: 10.1080/10799890802379410

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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