Effect of ambient extracellular glutamate on Drosophila glutamate receptor trafficking and function.

Abstract excerpt

Measurements suggest that the hemolymph glutamate concentrations in Drosophila are relatively high. This raises the possibility that extracellular glutamate could be an important regulator of glutamatergic transmission in vivo. Using voltage clamp electrophysiology, we found that synaptic currents in D. melanogaster larval neuromuscular junctions are reduced by extracellular glutamate (EC50: approximately 0.4...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Biophysics
• Share to Electric Stimulation