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Article

The postsynaptic glutamate receptor subunit DGluR-IIA mediates long-term plasticity in Drosophila.

The Journal of neuroscience : the official journal of the Society for Neuroscience - 1 Sept 2002

Sigrist Stephan J, Thiel Philippe R, Reiff Dierk F, Schuster Christoph M

Abstract excerpt

The developing neuromuscular junctions (NMJs) of Drosophila larvae can undergo long-term strengthening of signal transmission, a process that has been shown recently to involve local subsynaptic protein synthesis and that is associated with an elevated synaptic accumulation of the postsynaptic glutamate receptor subunit DGluR-IIA. To analyze the role of altered postsynaptic glutamate receptor expression during...

Topics

Animals
Animals, Genetically Modified
Cell Adhesion Molecules, Neuronal
Drosophila
Gene Dosage
Gene Expression
In Vitro Techniques
Larva
Long-Term Potentiation
Muscles

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Neuromuscular Junction

Neuronal Plasticity

Patch-Clamp Techniques

Phenotype

Poly(A)-Binding Proteins

Presynaptic Terminals

Protein Subunits

RNA-Binding Proteins

Source

Open in PubMed Open full text

Identifiers

PMID: 12196557
PMCID: PMC6757995

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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