Article

Excess glutamate release triggers subunit-specific homeostatic receptor scaling

2022-05-04

Abstract excerpt

<h4>ABSTRACT</h4> Ionotropic glutamate receptors (GluRs) are targets for modulation in Hebbian and homeostatic synaptic plasticity and are remodeled by development, experience, and disease. Although much is known about activity-dependent mechanisms that regulate GluR composition and abundance, the role of glutamate itself in these processes is unclear. To determine how glutamate sculpts GluR receptive fields, we...

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Literature Corpus work: f6eaaf63-e495-5e66-8186-ade15ce8f773
DOI: 10.1101/2022.05.03.490370

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