Article
Absence of junctional glutamate receptor clusters in Drosophila mutants lacking spontaneous transmitter release.
Science (New York, N.Y.) - 20 Jul 2001
Saitoe M, Schwarz T L, Umbach J A, Gundersen C B, Kidokoro Y
Abstract excerpt
Little is known about the functional significance of spontaneous miniature synaptic potentials, which are the result of vesicular exocytosis at nerve terminals. Here, by using Drosophila mutants with specific defects in presynaptic function, we found that glutamate receptors clustered normally at neuromuscular junctions of mutants that retained spontaneous transmitter secretion but had lost the ability to release...
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