Article
Drosophila glial glutamate transporter Eaat1 is regulated by fringe-mediated notch signaling and is essential for larval locomotion.
The Journal of neuroscience : the official journal of the Society for Neuroscience - 27 Oct 2010
Stacey Stephanie M, Muraro Nara I, Peco Emilie, Labbé Alain, Thomas Graham B, Baines Richard A, van Meyel Donald J
Abstract excerpt
In the mammalian CNS, glial cells expressing excitatory amino acid transporters (EAATs) tightly regulate extracellular glutamate levels to control neurotransmission and protect neurons from excitotoxic damage. Dysregulated EAAT expression is associated with several CNS pathologies in humans, yet...
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