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Article

Regulated lysosomal trafficking as a mechanism for regulating GABAA receptor abundance at synapses in Caenorhabditis elegans.

Molecular and cellular neurosciences - 1 Aug 2010

Davis Kathleen M, Sturt Brianne L, Friedmann Andrew J, Richmond Janet E, Bessereau Jean-Louis, Grant Barth D, Bamber Bruce A

Abstract excerpt

GABA(A) receptor plasticity is important for both normal brain function and disease progression. We are studying GABA(A) receptor plasticity in Caenorhabditis elegans using a genetic approach. Acute exposure of worms to the GABA(A) agonist muscimol hyperpolarizes postsynaptic cells, causing paral...

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Identifiers

PMID: 20403442
DOI: 10.1016/j.mcn.2010.04.002

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-20403442-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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