Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

repfdr: a tool for replicability analysis for genome-wide association studies.

Bioinformatics (Oxford, England) - 15 Oct 2014

Heller Ruth, Yaacoby Shay, Yekutieli Daniel

Abstract excerpt

MOTIVATION: Identification of single nucleotide polymorphisms that are associated with a phenotype in more than one study is of great scientific interest in the genome-wide association studies (GWAS) research. The empirical Bayes approach for discovering whether results have been replicated acros...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Bayes Theorem
Share to Biostatistics
Share to Genome-Wide Association Study

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Meta-Analysis as Topic

Share to Phenotype

Share to Polymorphism, Single Nucleotide

Source

Identifiers

PMID: 25012182
DOI: 10.1093/bioinformatics/btu434

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-25012182-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

repfdr: a tool for replicability analysis for genome-wide association studies.PMID 25012182Read ↗

What is the probability of replicating a statistically significant association in genome-wide association studies?Semantic proximity Read ↗

Power estimation and sample size determination for replication studies of genome-wide association studies.Semantic proximity Read ↗

A powerful approach to identify replicable variants in genome-wide association studies.Semantic proximity Read ↗

Model-based assessment of replicability for genome-wide association meta-analysis.Semantic proximity Read ↗

What Do We Mean by ‘Replication’ and ‘Validation’ in Genome-Wide Association Studies?Semantic proximity Read ↗

Reproducibility in the UK biobank of genome-wide significant signals discovered in earlier genome-wide association studies.Semantic proximity Read ↗

Is replication the gold standard for validating genome-wide association findings?Semantic proximity Read ↗

Effectiveness of strategies to increase the validity of findings from association studies: size vs. replication.Semantic proximity Read ↗

Statistical Correction of the Winner’s Curse Explains Replication Variability in Quantitative Trait Genome-Wide Association StudiesSemantic proximity Read ↗

The Phenotype-Genotype Reference Map: Improving biobank data science through replicationSemantic proximity Read ↗

A flexible genome-wide bootstrap method that accounts for ranking and threshold-selection bias in GWAS interpretation and replication study design.Semantic proximity Read ↗

Efficient replication of over 180 genetic associations with self-reported medical data.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.