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Article

Lipopolysaccharide-induced immune responses in relation to the TLR4(Asp299Gly) gene polymorphism.

Clinical and vaccine immunology : CVI - 1 Dec 2008

Lundberg Anna, Wikberg Lars Andersson, Ilonen Jorma, Vaarala Outi, Böttcher Malin Fagerås

Abstract excerpt

Altered microbial exposure is a possible explanation for the increase of allergies in the Western world. However, genetic factors influence microbially induced immune responses. We have investigated the TLR4(Asp299Gly) gene polymorphism and its possible association with receptor expression of circulating peripheral blood monocytes and the in vitro cytokine responses and phosphorylation of intracellular signaling...

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Source

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Identifiers

PMID: 18927069
DOI: 10.1128/CVI.00241-08
PMCID: PMC2593161

Genes

TLR4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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