Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Systemic responsiveness to lipopolysaccharide and polymorphisms in the toll-like receptor 4 gene in human beings.

The Journal of allergy and clinical immunology - 1 Nov 2003

Michel Olivier, LeVan Tricia D, Stern Debbie, Dentener Mieke, Thorn Jörgen, Gnat Daniele, Beijer M Lena, Cochaux Pascale, Holt Patrick G, Martinez Fernando D, Rylander Ragnar

Abstract excerpt

BACKGROUND: The response to lipopolysaccharide exposure is highly variable and might be a result of genetic diversity between individuals. The toll-like receptor 4 (TLR-4) is the principal receptor for lipopolysacharide. OBJECTIVES: We investigated the association between single-nucleotide polymo...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Acute-Phase Proteins
Share to Administration, Inhalation

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to C-Reactive Protein

Share to Leukocyte Count

Share to Lipopolysaccharides

Share to Receptors, Cell Surface

Share to Toll-Like Receptor 4

Share to Toll-Like Receptors

Source

Identifiers

PMID: 14610481
DOI: 10.1016/j.jaci.2003.05.001

Genes

TLR4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026. Prepared record publication-14610481-2026-09-01.1. Manifest publication-graph-cohort-2026-09-01.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 1 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Systemic responsiveness to lipopolysaccharide and polymorphisms in the toll-like receptor 4 gene in human beings.PMID 14610481Read ↗

The role of TLR4 in endotoxin responsiveness in humans.Semantic proximity Read ↗

TLR4 mutations are associated with endotoxin hyporesponsiveness in humans.Semantic proximity Read ↗

The TLR4 +896 polymorphism is not associated with lipopolysaccharide hypo-responsiveness in leukocytes.Semantic proximity Read ↗

Lipopolysaccharide-induced immune responses in relation to the TLR4(Asp299Gly) gene polymorphism.Semantic proximity Read ↗

Monocytes heterozygous for the Asp299Gly and Thr399Ile mutations in the Toll-like receptor 4 gene show no deficit in lipopolysaccharide signalling.Semantic proximity Read ↗

Polymorphisms of TLR4: rapid genotyping and reduced response to lipopolysaccharide of TLR4 mutant alleles.Semantic proximity Read ↗

Effects of Lipopolysaccharide-Binding Protein (LBP) Single Nucleotide Polymorphism (SNP) in Infections, Inflammatory Diseases, Metabolic Disorders and Cancers.Semantic proximity Read ↗

The role of lipopolysaccharide in the development of atopy in humans.Semantic proximity Read ↗

Single nucleotide polymorphisms of Toll-like receptors and susceptibility to infectious disease.Semantic proximity Read ↗

The toll-like receptor 4 Asp299Gly variant: no influence on LPS responsiveness or susceptibility to pulmonary tuberculosis in The Gambia.Semantic proximity Read ↗

TLR4 polymorphism and haplotype are associated with obesity and lipid profile in young population: a pilot study.Semantic proximity Read ↗

Functional consequences of the Asp299Gly Toll-like receptor-4 polymorphism.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.