Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Topics Community

Article

Genetic variation in Toll-like receptor signalling and the risk of inflammatory and immune diseases.

Journal of innate immunity - 1 Jan 2009

Corr Sinead C, O'Neill Luke A J

Abstract excerpt

There has been growing interest in the role of host genetic factors in humans and susceptibility to infectious and inflammatory diseases. Genetic variation in Toll-like receptors (TLRs), key innate immune receptors or their signalling molecules, have been described. Variation in certain TLRs has been linked to disease susceptibility. This genetic variation can result in an altered immune response to pathogenic...

Topics

Animals
Female
Genetic Variation
Humans
Immune System Diseases
Immunity, Innate
Inflammation
Male
Mice
Toll-Like Receptors

Source

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 20375592
DOI: 10.1159/000200774

Genes

TLR2
TLR4
IRAK4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

0

discussions

0

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Genetic variation in Toll-like receptor signalling and the risk of inflammatory and immune diseases.PMID 20375592Read ↗

Genetic variation in Toll-like receptors and disease susceptibility.Semantic proximity Read ↗

Toll-like receptor polymorphisms and susceptibility to human disease.Semantic proximity Read ↗

The Effect of Toll-Like Receptors and Toll-Like Receptor Genetics in Human DiseaseSemantic proximity Read ↗

TLR4 polymorphisms and disease susceptibility.Semantic proximity Read ↗

Single nucleotide polymorphisms of Toll-like receptors and susceptibility to infectious diseases.Semantic proximity Read ↗

Association of TLR1, TLR2, TLR4, TLR6, and TIRAP polymorphisms with disease susceptibility.Semantic proximity Read ↗

Toll-like receptor polymorphisms, inflammatory and infectious diseases, allergies, and cancer.Semantic proximity Read ↗

Relevance of single-nucleotide polymorphisms in human TLR genes to infectious and inflammatory diseases and cancer.Semantic proximity Read ↗

Single nucleotide polymorphisms of Toll-like receptors and susceptibility to infectious disease.Semantic proximity Read ↗

Single nucleotide polymorphisms of Toll-like receptors and susceptibility to infectious diseaseSemantic proximity Read ↗

Toll‐like receptor polymorphism in host immune response to infectious diseases: A reviewSemantic proximity Read ↗

Genetic variations in toll-like receptor pathway genes influence asthma and atopy.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.