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Article

A TLR4 polymorphism is associated with asthma and reduced lipopolysaccharide-induced interleukin-12(p70) responses in Swedish children.

The Journal of allergy and clinical immunology - 1 Sept 2004

Fagerås Böttcher Malin, Hmani-Aifa Mounira, Lindström Anna, Jenmalm Maria Christina, Mai Xiao-Mei, Nilsson Lennart, Zdolsek Helena Aniansson, Björkstén Bengt, Söderkvist Peter, Vaarala Outi

Abstract excerpt

BACKGROUND: Bacterial signals play an important role in the maturation of the immune system. Polymorphisms in genes coding for receptors to bacterial components can alter the immune responsiveness of the host to microbial agents and may indicate the development of aberrant immune responses that are associated with immune-mediated diseases such as atopic diseases. OBJECTIVE: The study's objective was to...

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Identifiers

PMID: 15356557
DOI: 10.1016/j.jaci.2004.04.050

Genes

TLR4

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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