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Article

Frequent mutations and amplifications of the PIK3CA gene in pituitary tumors.

Endocrine-related cancer - 1 Mar 2009

Lin Yong, Jiang Xiaofei, Shen Ye, Li Min, Ma Huili, Xing Mingzhao, Lu Yuan

Abstract excerpt

Genetic alterations in the PIK3CA gene of the phosphoinositide 3-kinase (PI3K)/AKT pathway have been found in many human tumors, but they have not been explored in pituitary tumors. We undertook the present study to explore mutations and amplifications of the PIK3CA gene in pituitary tumors. DNA sequencing and real-time quantitative PCR were used to examine mutations and amplifications respectively, on genomic...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Gene Expression Regulation, Enzymologic

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Source

Identifiers

PMID: 18852163
DOI: 10.1677/ERC-08-0167

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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