Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

<i>PIK3CA</i> mutation is an oncogenic aberration at advanced stages of oral squamous cell carcinoma

17 Oct 2006

Abstract excerpt

Phosphatidylinositol 3-kinases (PI3K) are a group of heterodimeric lipid kinases that regulate many cellular processes. Gene amplification and somatic mutations mainly within the helical (exon 9) and kinase (exon 20) domains of PIK3CA, which encode the 110-kDa catalytic subunit of PI3K and are mapped to 3q26, have been reported in various human cancers. Herein, 14 human oral squamous cell carcinoma (OSCC) cell...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Chronic Lymphocytic Leukemia Research
Share to PI3K/AKT/mTOR signaling in cancer
Share to Protein Degradation and Inhibitors

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 17052259
DOI: 10.1111/j.1349-7006.2006.00343.x

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

<i>PIK3CA</i> mutation is an oncogenic aberration at advanced stages of oral squamous cell carcinomaPMID 17052259Read ↗

Genetic alterations of the PIK3CA oncogene in human oral squamous cell carcinoma in an Indian population.Semantic proximity Read ↗

<i>PIK3CA</i> Mutations in Head and Neck Squamous Cell CarcinomaSemantic proximity Read ↗

Oncogenic mutations of the PIK3CA gene in head and neck squamous cell carcinomas.Semantic proximity Read ↗

Analysis of PIK3CA and Akt/protein kinase B in head and neck squamous cell carcinoma.Semantic proximity Read ↗

<i>PIK3CA</i> mutations in nasopharyngeal carcinomaSemantic proximity Read ↗

Novel mutations of PIK3CA gene in head and neck squamous cell carcinoma.Semantic proximity Read ↗

Identification of <i>PAK4</i> as a putative target gene for amplification within 19q13.12‐q13.2 in oral squamous‐cell carcinomaSemantic proximity Read ↗

<i>PIK3CA</i> Mutation Is Associated with a Favorable Prognosis among Patients with Curatively Resected Esophageal Squamous Cell CarcinomaSemantic proximity Read ↗

Mutational status of PIK3ca oncogene in oral cancer-In the new age of PI3K inhibitors.Semantic proximity Read ↗

Absence of hotspot mutations in exons 9 and 20 of the PIK3CA gene in human oral squamous cell carcinoma in the Greek population.Semantic proximity Read ↗

Understanding PI3K/Akt/mTOR signaling in squamous cell carcinoma: mutated PIK3CA as an example.Semantic proximity Read ↗

Frequent mutation of the PIK3CA gene in ovarian and breast cancers.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.