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Article

High molecular weight FGF2: the biology of a nuclear growth factor.

Cellular and molecular life sciences : CMLS - 1 Jan 2009

Chlebova K, Bryja V, Dvorak P, Kozubik A, Wilcox W R, Krejci P

Abstract excerpt

Fibroblast growth factor 2 (FGF2) is one of the most studied growth factors to date. Most attention has been dedicated to the smallest, 18 kDa FGF2 variant that is released by cells and acts through activation of cell-surface FGF-receptor tyrosine kinases. There are, however, several higher molecular weight (HMW) variants of FGF2 that rarely leave their producing cells, are retained in the nucleus and act...

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Source

Open in PubMed Open full text

Identifiers

PMID: 18850066
DOI: 10.1007/s00018-008-8440-4
PMCID: PMC3229932

Genes

FGF2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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