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Article

Molecular mechanisms of fibroblast growth factor signaling in physiology and pathology.

Cold Spring Harbor perspectives in biology - 1 Jun 2013

Belov Artur A, Mohammadi Moosa

Abstract excerpt

Fibroblast growth factors (FGFs) signal in a paracrine or endocrine fashion to mediate a myriad of biological activities, ranging from issuing developmental cues, maintaining tissue homeostasis, and regulating metabolic processes. FGFs carry out their diverse functions by binding and dimerizing FGF receptors (FGFRs) in a heparan sulfate (HS) cofactor- or Klotho coreceptor-assisted manner. The accumulated wealth...

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Identifiers

PMID: 23732477
DOI: 10.1101/cshperspect.a015958
PMCID: PMC3660835

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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