Article
Complexity of FGF receptors: genetic basis for structural diversity and functional specificity.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology - 1 Dec 1992
Givol D, Yayon A
Abstract excerpt
Since 1989, the receptors for fibroblast growth factors (FGFs) were cloned and characterized as a subgroup of the family of receptor tyrosine kinases. Four FGF receptor genes were identified, all of which encode membrane-bound glycoproteins containing three immunoglobulin (Ig) -like domains at the extracellular region, where only two of these domains are involved in ligand binding. Three unique features...
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