Article
Six-month, prospective, longitudinal, open-label caffeine and dextromethorphan phenotyping study in children with growth hormone deficiency receiving recombinant human growth hormone replacement.
Clinical therapeutics - 1 Sept 2008
Kennedy Mary Jayne, Davis Daniel A, Smith Ned, Gaedigk Andrea, Pearce Robin E, Kearns Gregory L
Abstract excerpt
BACKGROUND: Recombinant human growth hormone (r-hGH) is increasingly being used in children. Although growth hormone (GH) may alter the clearance of concomitantly administered medications, its effects on individual drug-metabolizing enzymes in children have not been characterized. OBJECTIVE: The...
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