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Article

LKB1 induces apical trafficking of Silnoon, a monocarboxylate transporter, in Drosophila melanogaster.

The Journal of cell biology - 6 Oct 2008

Jang Cholsoon, Lee Gina, Chung Jongkyeong

Abstract excerpt

Silnoon (Sln) is a monocarboxylate transporter (MCT) that mediates active transport of metabolic monocarboxylates such as butyrate and lactate. Here, we identify Sln as a novel LKB1-interacting protein using Drosophila melanogaster genetic modifier screening. Sln expression does not affect cell cycle progression or cell size but specifically enhances LKB1-dependent apoptosis and tissue size reduction. Conversely,...

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Identifiers

PMID: 18838551
DOI: 10.1083/jcb.200807052
PMCID: PMC2557035

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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