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Article

Drosophila LKB1 is required for the assembly of the polarized actin structure that allows spermatid individualization.

PloS one - 1 Jan 2017

Couderc Jean-Louis, Richard Graziella, Vachias Caroline, Mirouse Vincent

Abstract excerpt

In mammals, a testis-specific isoform of the protein kinase LKB1 is required for spermiogenesis, but its exact function and specificity are not known. Human LKB1 rescues the functions of Drosophila Lkb1 essential for viability, but these males are sterile, revealing a new function for this genes in fly. We also identified a testis-specific transcript generated by an alternative promoter and that only differs by a...

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Identifiers

PMID: 28767695
DOI: 10.1371/journal.pone.0182279
PMCID: PMC5540607

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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