Article
Overexpression of Larp4B downregulates dMyc and reduces cell and organ sizes in Drosophila.
Biochemical and biophysical research communications - 4 Mar 2018
Funakoshi Masabumi, Tsuda Manabu, Muramatsu Keigo, Hatsuda Hiroshi, Morishita Shinichi, Aigaki Toshiro
Abstract excerpt
Regulation of cell and organ sizes is fundamental for all organisms, but its molecular basis is not fully understood. Here we performed a gain-of-function screen and identified larp4B whose overexpression reduces cell and organ sizes in Drosophila melanogaster. Larp4B is a member of La-related proteins (LARPs) containing an LA motif and an adjacent RNA recognition motif (RRM), and play diverse roles in RNA...
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