Article
Genetic susceptibility to benzene toxicity in humans.
Journal of toxicology and environmental health. Part A - 1 Jan 2008
Garte Seymour, Taioli Emanuela, Popov Todor, Bolognesi Claudia, Farmer Peter, Merlo Franco
Abstract excerpt
Human metabolism of benzene involves pathways coded for by polymorphic genes. To determine whether the genotype at these loci might influence susceptibility to the adverse effects of benzene exposure, 208 Bulgarian petrochemical workers and controls, whose exposure to benzene was determined by active personal sampling, were studied. The frequency of DNA single-strand breaks (DNA-SSB) was determined by alkaline...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
