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Article

Genetic variations in benzene metabolism and susceptibility to multiple myeloma.

Leukemia research - 1 Jun 2007

Lincz Lisa F, Scorgie Fiona E, Robertson Richard, Enno Arno

Abstract excerpt

We have previously shown that deficiency in the biotransformation enzyme glutathione-S-transferase theta (GSTT1) is a risk factor for multiple myeloma (MM). The present case-control study of 102 MM patients and 205 controls revealed a significant trend in increasing risk of MM with inheritance of multiple putative 'high risk' genetic variants in related pathways of benzene detoxification. Individuals who carried...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 16949155
DOI: 10.1016/j.leukres.2006.07.012

Genes

GSTT1
NQO1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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