Article
Exposure to low environmental levels of benzene: evaluation of micronucleus frequencies and S-phenylmercapturic acid excretion in relation to polymorphisms in genes encoding metabolic enzymes.
Mutation research - 3 Feb 2011
Angelini Sabrina, Kumar Rajiv, Bermejo Justo Lorenzo, Maffei Francesca, Barbieri Anna, Graziosi Francesca, Carbone Fabio, Cantelli-Forti Giorgio, Violante Francesco Saverio, Hemminki Kari, Hrelia Patrizia
Abstract excerpt
An integrated approach based on environmental and biological monitoring, including the analysis of biomarkers of exposure [excretion of S-phenylmercapturic acid (S-PMA)], early biological effects [micronucleus (MN) frequency] and susceptibility (genetic polymorphisms), was applied to characterize benzene exposure in a group of 70 traffic policemen and 40 employees of the city of Bologna, Italy. Median personal...
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