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Article

Epigenetic alterations in colorectal cancer: the CpG island methylator phenotype.

Histology and histopathology - 1 May 2013

Bae Jeong Mo, Kim Jung Ho, Kang Gyeong Hoon

Abstract excerpt

DNA methylation is one of the key mechanisms of epigenetic modification, and genome-wide hypomethylation and CpG island hypermethylation are characteristics of cancer cells. The CpG island methylator phenotype (CIMP) is a distinctive subtype of colorectal cancers (CRCs) that show concordant hypermethylation of numerous promoter CpG island loci. CIMP-positive CRCs are associated with a proximal location in the...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Identifiers

PMID: 23341177
DOI: 10.14670/HH-28.585

Genes

BRAF

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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