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Article

Glucosidase-beta variations and Lewy body disorders.

Parkinsonism & related disorders - 1 Jul 2009

Farrer Matthew J, Williams Lindsey N, Algom Avi A, Kachergus Jennifer, Hulihan Mary M, Ross Owen A, Rajput Alex, Papapetropoulos Spiridon, Mash Deborah C, Dickson Dennis W

Abstract excerpt

It has been proposed that there is an increased frequency of glucosidase-beta mutations in Lewy body disorders. Our comprehensive DNA sequencing approach found a small number of glucosidase-beta mutations in 101 neuropathologically defined Lewy body disease cases (3%) compared to 99 healthy post-mortem controls (1%); odds ratio 3.0 (95% CI: 0.3-29, p=0.3). All three affected carriers were classified as diffuse...

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Identifiers

PMID: 18829375
DOI: 10.1016/j.parkreldis.2008.08.004
PMCID: PMC2970615

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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