Article
Recent advances in the genetics of dementia with lewy bodies.
Current neurology and neuroscience reports - 1 May 2008
Bonifati Vincenzo
Abstract excerpt
In the past few years, mutations have been identified in the genes encoding alpha-synuclein, leucine-rich repeat kinase 2, and glucocerebrosidase in some patients with dementia with Lewy bodies (DLB). Furthermore, a novel locus for familial DLB has been mapped to chromosome 2q35-q36. Collectively, these discoveries highlight a substantial overlap between the known genetic determinants of Parkinson's disease and...
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